Which lipoprotein transports cholesterol from tissues to the liver for breakdown?

• A. High Density Lipoproteins
• B. Low Density Lipoproteins
• C. Chylomicrons
• D. Very Low Density Lipoproteins

Answer: (A)

High-density lipoproteins are responsible for reverse cholesterol transport, moving cholesterol from tissues back to the liver for breakdown and excretion. This helps regulate cholesterol levels and protect against buildup in arteries. HDL are small and dense, rich in apolipoprotein A-I, and deliver cholesterol to the liver where it’s converted to bile or excreted. By contrast, other lipoproteins have different roles: low-density lipoproteins carry cholesterol from the liver to tissues, chylomicrons transport dietary lipids from the gut to tissues, and very low-density lipoproteins carry triglycerides from the liver to tissues (and can become LDL in the bloodstream).